Overview

UC involves the inner lining of the large intestine. It is autoimmune in nature and often follows a relapsing-remitting course. It increases risk for colon cancer with long-standing disease.

Causes

• Autoimmune response
• Genetic predisposition
• Environmental triggers
• Altered gut microbiota

Symptoms

• Bloody diarrhea, urgency
• Abdominal cramps
• Fatigue, weight loss
• Rectal bleeding
• Fever (in severe flares)

Treatment: Modern Medicine

• Diagnosis: Colonoscopy with biopsy, stool tests, CRP
• Treatment:
  • 5-ASA drugs (Mesalamine)
  • Steroids for flares
  • Immunosuppressants (Azathioprine)
  • Biologics (Infliximab, Adalimumab)
  • Surgery (Colectomy for severe cases)

Treatment: Traditional Medicine

• Ayurveda: Kutaja, Bilva, Nagaramustaka for diarrhea; Takra (buttermilk) therapy
• Siddha: Decoctions for gut inflammation
• Unani: Gut tonics and mufarreh drugs
• TCM: Huang Lian, Bai Zhu for intestinal heat and dampness
• Homeopathy: Mercurius corrosivus, Aloe socotrina
• Nutraceuticals: Probiotics, Omega-3, Curcumin, L-glutamine

Caution

• Monitor for anemia and dehydration
• Regular colonoscopy for cancer screening

Prevention

• Anti-inflammatory diet (low FODMAP or SCD)
• Stress management
• Avoid NSAIDs