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Congenital megacolon or Hirschsprung's disease

Overview

Congenital megacolon, is a condition that affects the large intestine (colon) and causes problems with passing stool. It's a congenital condition, meaning it's present at birth, and occurs when certain nerve cells in the colon are missing.

These nerve cells, called ganglion cells, are responsible for controlling the muscles that push stool through the intestines. In this, the affected segment of the colon lacks these ganglion cells, leading to a narrowing or obstruction of the colon.

Causes

  • Genetic factors
  • Embryological development
  • Environmental factors
  • Associated conditions: such as Down syndrome, Waardenburg syndrome,and multiple endocrine neoplasia type 2.
  • Symptoms

  • Failure to pass meconium: Meconium is the dark, sticky stool that newborns typically pass within the first 24 to 48 hours after birth. 
  • Chronic constipation
  • Abdominal distension
  • Vomiting
  • Poor feeding and weight gain
  • Foul-smelling stool
  • Enterocolitis
  • Treatment: Modern Medicine

  • Pull-through procedure
  • Nutritional support
  • Staged repair
  • Bowel management
  • Treatment: Traditional Medicine

    • Dietary modifications
    • Medications: In some cases, laxatives or stool softeners.
    • Acupuncture
    • Caution

    • Potential limitations
    • Risks and side effects: Some traditional or non-surgical treatments may carry risks or side effects.
    • Prevention

    • Genetic counseling
    • Prenatal screening
    • Early diagnosis and treatment

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